Luminescent Reagents Superoxide detection
AB-2980 NIR-CLA
Chemiluminescence Reagent
The novel probe for detection of active oxygen is emitted near-infrared light of 800nm by reaction with superoxide.
![Monitoring of active oxygen in human blood. It detected amount of O2- generated by stimulation with zymosan against human blood sample in using NIR-CLA, MCLA and Luminol. Monitoring of active oxygen in human blood. It detected amount of O2- generated by stimulation with zymosan against human blood sample in using NIR-CLA, MCLA and Luminol.](https://www.atto.co.jp/var/ezwebin_site/storage/images/products/reagents/superoxidedetection/ab-2980/27430-16-eng-GB/NIR-CLA_medium.jpg)
Monitoring of active oxygen in human blood
It detected amount of O2- generated by stimulation with zymozan against human blood sample in using NIR-CLA, MCLA and Luminol.
Features
The novel probe for detection of active oxygen is emitted near-infrared light of 800nm by reaction with superoxide.
Since hemoglobin absorbs the light below 650nm, other probes such as MCLA or Luminol which has a peak in under 500nm can not be detected their signals in blood sample.
NIR-CLA probe enables to detect superoxide in whole blood sample very efficiently. The signal of NIR-CLA probe in blood sample is transmitted abount 20% of that in PBS, although it is affected from absorption by hemoglobin.
Specifications
Documents
AB-2980 NIR-CLA Brochure |
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AB-2980 NIR-CLA Manual |
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